Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009768 | 0.84 | DAO (0.46) | DAO | |
| SCHEMBL75926 | 0.83 | — | — | |
| SCHEMBL4700498 | 0.79 | — | — | |
| SCHEMBL4581201 | 0.79 | — | — | |
| SCHEMBL1680413 | 0.79 | — | — | |
| SCHEMBL25423722 | 0.79 | — | — | |
| SCHEMBL23079299 | 0.79 | — | — | |
| SCHEMBL447798 | 0.79 | — | — | |
| SCHEMBL13754484 | 0.79 | DAO (0.30) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL1706879 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277420-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-01 | — | — | US | disclosed |
| US-8212055-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-07-03 | — | — | US | disclosed |
| WO-2012033916-A1 | METHOD FOR TREATING CHRONIC PAIN | SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE (US) | 2012-03-15 | — | — | WO | disclosed |
| US-20100204465-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-08-12 | — | — | US | disclosed |
| US-7678900-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090069558-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-12 | — | — | US | disclosed |
| US-7470785-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069558-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | DAO 994/4885HDAC8 4452/4885HDAC6 4272/4885 |
| US-20100204465-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | DAO 994/4885HDAC8 4452/4885HDAC6 4272/4885 |
| US-20120277420-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | DAO 994/4885HDAC8 4452/4885HDAC6 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.