Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802204 | 0.83 | TSHR (0.50) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL1681118 | 0.79 | TSHR (0.51) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL28376224 | 0.78 | TSHR (0.50) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL5873224 | 0.76 | TSHR (0.49) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL3249145 | 0.76 | CYP2C9 (0.52) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL10628291 | 0.75 | TSHR (0.48) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL5873170 | 0.74 | CYP2C19 (0.47) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL27427456 | 0.73 | CYP2C9 (0.49) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| SCHEMBL6135938 | 0.70 | CYP2C19 (0.46) | CYP2C9CYP2C19CYP2D6TSHRDAO | |
| Thiophene Carboxylic Acid SCHEMBL4617799 | 0.70 | DAO (0.76) | CYP2C9CYP2C19CYP2D6TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817281-B1 | Organic electroluminescent device with an inorganic electron-conducting layer | PHILIPS INTELLECTUAL PROPERTY (DE) | 2008-10-15 | — | — | EP | disclosed |
| EP-0697744-B1 | Organic electroluminescent device | PHILIPS PATENTVERWALTUNG (DE) | 2000-01-05 | — | — | EP | disclosed |
| EP-0817281-A2 | Organic electroluminescent device with an inorganic electron-conducting layer | Philips Patentverwaltung GmbH (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0697744-A1 | Organic electroluminescent device | Philips Patentverwaltung GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |