Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937375 | 0.84 | RAB9A (0.58) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL1681118 | 0.83 | TSHR (0.51) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL27427456 | 0.83 | CYP2C9 (0.49) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28376224 | 0.81 | TSHR (0.50) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL2802204 | 0.81 | TSHR (0.50) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL5873224 | 0.80 | TSHR (0.49) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3839189 | 0.79 | DAO (0.55) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10628291 | 0.79 | TSHR (0.48) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28843649 | 0.78 | RAB9A (0.49) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL5873170 | 0.78 | CYP2C19 (0.47) | CYP2C9TSHRCYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110800150-A | Non-aqueous electrolyte and electrolytic solution containing electrolyte stabilizing material, secondary battery containing the same, and use thereof | 株式会社村田制作所 | 2020-02-14 | — | — | CN | disclosed |
| EP-3311813-B1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | DART NEUROSCIENCE CAYMAN LTD (KY) | 2019-08-07 | — | — | EP | disclosed |
| EP-3311813-B1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | DART NEUROSCIENCE CAYMAN LTD (KY) | 2019-08-07 | — | — | EP | disclosed |
| US-10053467-B2 | Therapeutic isoxazole compounds | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2018-08-21 | — | — | US | disclosed |
| EP-3311813-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | Dart Neuroscience (Cayman) Ltd (KY) | 2018-04-25 | — | — | EP | disclosed |
| EP-3311813-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | Dart Neuroscience (Cayman) Ltd (KY) | 2018-04-25 | — | — | EP | disclosed |
| EP-2182809-B1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | DART NEUROSCIENCE (CAYMAN) LTD (KY) | 2018-01-17 | — | — | EP | disclosed |
| EP-2182809-B1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | DART NEUROSCIENCE (CAYMAN) LTD (KY) | 2018-01-17 | — | — | EP | disclosed |
| US-20170204111-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | DART NEUROSCIENCE LLC | 2017-07-20 | — | — | US | disclosed |
| US-20170204111-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | DART NEUROSCIENCE LLC | 2017-07-20 | — | — | US | disclosed |
| WO-2009029632-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090062252-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090062252-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | US | disclosed |
| EP-1559754-B1 | INK COMPOSITION | NIPPON KAYAKU KK (JP) | 2006-12-06 | — | — | EP | disclosed |
| US-20060001006-A1 | Ink compositon | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1559754-A1 | INK COMPOSITION | Nippon Kayaku Kabushiki Kaisha (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20040082464-A1 | Complex polymerization catalysts for the homopolymerization of ethylene and for the copolymerization of ethylene | POLIMERI EUROPA S.P.A. (IT) | 2004-04-29 | — | — | US | disclosed |
| EP-1268500-B1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | POLIMERI EUROPA SPA (IT) | 2003-10-01 | — | — | EP | disclosed |
| EP-1268500-A1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | Polimeri Europa S.p.A. (IT) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074831-A1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | POLIMERI EUROPA S.P.A. (IT) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10053467-B2 | Therapeutic isoxazole compounds | MAOB, MAOA, XDH | CYP2C9 63/4885TSHR 1497/4885CYP2D6 130/4885 |
| US-20170204111-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | MAOB, MAOA, XDH | CYP2C9 63/4885TSHR 1497/4885CYP2D6 130/4885 |
| US-20090062252-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | MAOB, MAOA, XDH | CYP2C9 63/4885TSHR 1497/4885CYP2D6 130/4885 |
| US-20040082464-A1 | Complex polymerization catalysts for the homopolymerization of ethylene and for the copolymerization of ethylene | ETV6, MVD, ELL | CYP2C9 1139/4885TSHR 4714/4885CYP2D6 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.