Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268089 | 1.00 | REN (0.37) | RENUTS2RTSHRMAPTMEN1 | |
| SCHEMBL2339171 | 0.95 | MAPT (0.40) | RENUTS2RTSHRMAPTCYP3A4 | |
| SCHEMBL1037801 | 0.94 | REN (0.39) | RENUTS2RTSHRMAPTMEN1 | |
| SCHEMBL2341022 | 0.94 | UTS2R (0.37) | RENUTS2RTSHRMAPTCYP3A4 | |
| SCHEMBL2684184 | 0.91 | REN (0.40) | RENTSHRMAPTCYP3A4POLB | |
| SCHEMBL3469067 | 0.91 | REN (0.40) | RENTSHRMAPTCYP3A4POLB | |
| SCHEMBL4581822 | 0.91 | REN (0.36) | RENUTS2RTSHRMAPTMEN1 | |
| SCHEMBL3267997 | 0.91 | REN (0.36) | RENUTS2RTSHRMAPTMEN1 | |
| SCHEMBL3268975 | 0.91 | REN (0.34) | RENUTS2RTSHRMAPTCYP3A4 | |
| SCHEMBL3274201 | 0.90 | CYP3A4 (0.35) | RENUTS2RTSHRMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |