Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451271 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2HTR7 | |
| SCHEMBL4581560 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL451272 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL450561 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL1553141 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL452032 | 0.72 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL450965 | 0.72 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL451938 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL450328 | 0.70 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 | |
| SCHEMBL453890 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | X-CEPTOR THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | NR1H4, NR1H2, NR1H3 | ALDH1A1 3161/4885KDM4E 3717/4885MAPT 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.