SCHEMBL4581798

COCCCC(O[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]1c1ccc(OCCCOCc2ccccc2OC)cc1)c1ccc2c(c1)NC(=O)C2(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	20/20	0.39

▸	CYP3A4	P08684	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4582823	0.92	REN (0.38)	RENCYP3A4
SCHEMBL4526400	0.85	REN (0.39)	RENCYP3A4
SCHEMBL4582711	0.83	REN (0.39)	REN
SCHEMBL3066418	0.82	REN (0.41)	RENCYP3A4
SCHEMBL4581792	0.80	REN (0.41)	RENCYP3A4
SCHEMBL4609486	0.80	REN (0.41)	RENCYP3A4
SCHEMBL1039554	0.80	REN (0.47)	REN
SCHEMBL1036304	0.80	REN (0.44)	REN
SCHEMBL2340534	0.80	REN (0.46)	REN
SCHEMBL4583364	0.80	REN (0.46)	REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1908762-A2	Organic compounds	Speedel Experimenta AG (CH)	2008-04-09	—	—	EP	disclosed
EP-1908761-A1	Organic compounds	Speedel Experimenta AG (CH)	2008-04-09	—	—	EP	disclosed