SCHEMBL4582124

SCHEMBL4582124

NC(=O)CCC(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
KMT2A Q03164 3/20 0.45
CA2 P00918 2/20 0.45
MEN1 O00255 1/20 0.45
ALOX15 P16050 3/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
TAAR1 Q96RJ0 2/20 0.41
HTR3A P46098 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
HIF1A Q16665 1/20 0.41
GRM8 O00222 1/20 0.41
GRM4 Q14833 1/20 0.41
SRC P12931 1/20 0.40
SLC7A5 Q01650 1/20 0.40
NAALAD2 Q9Y3Q0 1/20 0.40
TDP1 Q9NUW8 3/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854656 0.90 CNR1 (0.45) CNR1CNR2KMT2ACA2MEN1
SCHEMBL223316 0.83 NAALAD2 (0.53) CNR1CNR2CA2ALOX15TSHR
SCHEMBL2091811 0.83 HRH1 (0.52) CNR1CNR2KMT2ALMNACYP1A2
SCHEMBL2862307 0.82 CACNA1B (0.54) KMT2AALOX15BLMPMP22CACNA1B
Hydrochloric Acid SCHEMBL28569021 0.82 HRH1 (0.50) CNR1CNR2KMT2ALMNACYP1A2
Hydrochloric Acid SCHEMBL7389220 0.81 CACNA1B (0.55) CACNA1BADORA3TBXA2RADRA1AOPRM1
SCHEMBL28355193 0.78 CNR1 (0.55) CNR1CNR2KMT2AMEN1CACNA1B
SCHEMBL1595841 0.78 ESR1 (0.50) CNR1CNR2KMT2ACA2MEN1
Propionic Acid SCHEMBL11111085 0.77 NAALAD2 (0.48) CNR1CNR2CA2ALOX15NAALAD2
SCHEMBL2538851 0.76 TBXAS1 (0.47) CNR1CNR2CA2SRCNAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312349-A1 METHOD OF MAKING AND USING MEMBRANE GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
US-20080207822-A1 COMPOSITION AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
US-20080203012-A1 MEMBRANE, APPARATUS, AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed