⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582307 | 1.00 | — | — | |
| SCHEMBL7118056 | 0.92 | POLB (0.33) | — | |
| SCHEMBL7129242 | 0.92 | — | — | |
| SCHEMBL7129237 | 0.92 | — | — | |
| SCHEMBL7118054 | 0.92 | POLB (0.33) | — | |
| SCHEMBL8693325 | 0.81 | POLB (0.37) | — | |
| SCHEMBL8693335 | 0.81 | POLB (0.37) | — | |
| Upenazime SCHEMBL1477985 | 0.76 | POLB (0.37) | — | |
| SCHEMBL15144439 | 0.74 | POLB (0.36) | — | |
| SCHEMBL15135657 | 0.74 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688313-B1 | LIGANDS AND METAL COMPLEXES THEREOF | BRACCO INT BV (NL) | 1998-04-08 | — | — | EP | claimed |
| CN-1122132-A | Ligands and metal complexes thereof | BRACCO INT BV (NL) | 1996-05-08 | — | — | CN | claimed |
| US-7399460-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2008-07-15 | — | — | US | disclosed |
| US-20070077197-A1 | Metal Complexes Derivatized with Folate for use in Diagnostic and Therapeutic Applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-04-05 | — | — | US | disclosed |
| US-7186397-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO SUISSE SA (CH) | 2001-06-21 | — | — | US | disclosed |
| US-6221334-B1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO RESEARCH USA, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6093382-A | A FOLATE-RECEPTOR BINDING LIGAND COMPRSING ONE OR MORE FOLATE BINDING GROUPS, ATLEAST ONE OF WHICH IS CONJUGATED THROUGH ALPHA CARBOXYLATE VIA A LINKING GROUP TO MACROCYCLIC OR NON MACROCYCLIC METAL CHELATING LIGAND RADICAL | BRACCO RESEARCH USA INC. (US) | 2000-07-25 | — | — | US | disclosed |