Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582351 | 1.00 | REN (0.34) | RENHRH1HRH2HRH3KCNH2 | |
| SCHEMBL4583362 | 0.96 | REN (0.34) | RENHRH1HRH2HRH3KCNH2 | |
| SCHEMBL4583366 | 0.96 | REN (0.34) | RENHRH1HRH2HRH3KCNH2 | |
| SCHEMBL4583824 | 0.94 | REN (0.33) | RENHRH1HRH2HRH3KCNH2 | |
| SCHEMBL4583822 | 0.94 | REN (0.33) | RENHRH1HRH2HRH3KCNH2 | |
| SCHEMBL4584456 | 0.94 | REN (0.33) | RENPPARGPPARDPPARA | |
| SCHEMBL4528639 | 0.92 | REN (0.36) | RENHRH3CYP3A4PPARGPPARD | |
| SCHEMBL4582973 | 0.90 | REN (0.44) | RENCYP3A4 | |
| SCHEMBL4582978 | 0.90 | REN (0.44) | RENCYP3A4 | |
| SCHEMBL4583012 | 0.89 | REN (0.37) | RENPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |