Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM6A | O15550 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034150 | 0.82 | SNCA (0.78) | SNCAAPPRAB9AHTTMAPT | |
| SCHEMBL8355851 | 0.77 | SNCA (0.62) | SNCAAPPRAB9AHTTMAPT | |
| SCHEMBL8355849 | 0.77 | SNCA (0.62) | SNCAAPPRAB9AHTTMAPT | |
| SCHEMBL6421503 | 0.74 | SNCA (0.64) | SNCAAPPHDAC3HDAC4HDAC1 | |
| SCHEMBL6421501 | 0.74 | SNCA (0.64) | SNCAAPPHDAC3HDAC4HDAC1 | |
| SCHEMBL22360047 | 0.74 | MEN1 (0.63) | SNCAAPPHDAC3HDAC4HDAC1 | |
| SCHEMBL21574848 | 0.71 | ESR1 (0.56) | SNCAAPPHDAC3HDAC4HDAC1 | |
| Benzoxazolinone SCHEMBL140087 | 0.69 | HDAC3 (0.56) | SNCAAPPHDAC3HDAC4HDAC1 | |
| Benzoxazolinone SCHEMBL31124589 | 0.69 | HDAC3 (0.56) | SNCAAPPHDAC3HDAC4HDAC1 | |
| SCHEMBL14190710 | 0.69 | HTT (0.56) | SNCAAPPHTTMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080008628-A1 | MICROFLUIDIC REACTION CHIP AND METHOD OF MANUFACTURING THE SAME | SAMSUNG ELECTRONICS CO., LTD (KR) | 2008-01-10 | — | — | US | disclosed |
| US-6140051-A | USE IN THE FIELD OF BIOLOGICAL ASSAYS | PROMEGA BIOSCIENCES, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1000042-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | Promega Biosciences, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-2000004007-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999003849-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 1999-01-28 | — | — | WO | disclosed |