Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355851 | 0.88 | SNCA (0.62) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL8355849 | 0.88 | SNCA (0.62) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL23111674 | 0.84 | MAPT (0.67) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL826090 | 0.84 | MAPT (0.67) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL28707498 | 0.84 | SNCA (0.65) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL29464223 | 0.84 | SNCA (0.65) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL9514854 | 0.83 | SNCA (0.64) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL9514858 | 0.83 | SNCA (0.64) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL4582552 | 0.82 | SNCA (0.56) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL2802355 | 0.81 | RAB9A (0.71) | SNCARAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140051-A | USE IN THE FIELD OF BIOLOGICAL ASSAYS | PROMEGA BIOSCIENCES, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1000042-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | Promega Biosciences, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-2000004007-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999003849-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 1999-01-28 | — | — | WO | disclosed |