Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583733 | 0.95 | F10 (0.44) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL8489014 | 0.86 | MMP2 (0.48) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL4583428 | 0.85 | F10 (0.43) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL4583782 | 0.84 | F10 (0.44) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL3314623 | 0.84 | F10 (0.42) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL13394894 | 0.82 | MMP2 (0.46) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL13372716 | 0.82 | F10 (0.47) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL4583712 | 0.81 | F10 (0.35) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL4441713 | 0.81 | F10 (0.35) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL13372852 | 0.81 | F10 (0.44) | F10LMNAMAPK1KMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |