SCHEMBL4582690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4584227	0.93	PDGFRB (0.38)	PDGFRBRXFP1MAPTLMNAKMT2A
	SCHEMBL4582435	0.92	HCRTR1 (0.41)	MAPTLMNAKMT2AMAPK14ALDH1A1
	SCHEMBL4582504	0.89	PDGFRB (0.44)	PDGFRBRXFP1MAPTLMNAKMT2A
	SCHEMBL4583950	0.88	PDGFRB (0.43)	PDGFRBRXFP1LMNAKMT2AKDR
	SCHEMBL4581836	0.86	JAK2 (0.43)	PDGFRBLMNAKMT2AMAPK14LCK
	SCHEMBL4583964	0.86	LMNA (0.39)	PDGFRBMAPTLMNAKMT2AMAPK14
	SCHEMBL4584330	0.85	HCRTR1 (0.41)	MAPTLMNAKMT2AALDH1A1HCRTR1
	SCHEMBL4583025	0.83	JAK2 (0.46)	MAPTKMT2AMAPK14JAK1ALDH1A1
	SCHEMBL4582550	0.83	MAPT (0.43)	PDGFRBMAPTKMT2AKDRALDH1A1
	SCHEMBL4582539	0.81	PDGFRB (0.44)	PDGFRBRXFP1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.