Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.57 |
| ▸ | HTR2C | P28335 | 6/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5122153 | 0.99 | MTNR1A (0.56) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| SCHEMBL3632637 | 0.89 | MTNR1A (0.66) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| SCHEMBL30448774 | 0.89 | MTNR1A (0.66) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL3326573 | 0.88 | MTNR1A (0.65) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| SCHEMBL4585508 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL5123674 | 0.83 | MTNR1A (0.52) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| SCHEMBL3635980 | 0.82 | MTNR1A (0.66) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| SCHEMBL4583437 | 0.81 | MTNR1A (0.83) | MTNR1AMTNR1BHTR2CNQO2 | |
| Hydrochloric Acid SCHEMBL1883403 | 0.81 | MTNR1A (0.64) | MTNR1AMTNR1BHTR2CADRA2AADRA1A | |
| SCHEMBL12505912 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2CADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900723-A1 | New naphthalene derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2008-03-19 | — | — | EP | disclosed |