SCHEMBL458291

SCHEMBL458291

O=C1CCC=CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11584271 0.96
SCHEMBL3395264 0.90 TRIM24 (0.62)
SCHEMBL3397675 0.90 TRIM24 (0.62)
SCHEMBL1566775 0.87
SCHEMBL16417514 0.87 TRIM24 (0.50)
SCHEMBL7909719 0.87 TRIM24 (0.47)
SCHEMBL1566776 0.87
SCHEMBL7917256 0.87
SCHEMBL16417515 0.85 TRIM24 (0.47)
SCHEMBL3393321 0.85 TRIM24 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020044102-A1 BROMINE FREE PREPARATION OF 5H-DIBENZO [A,D] CYCLOHEPTEN-5-ONE R L FINE CHEM PRIVATE LIMITED (IN) 2020-03-05 WO claimed
EP-0272621-B1 Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones BASF Aktiengesellschaft (DE) 1991-11-27 EP claimed
US-4845302-A Preparation of 5H-dibenzo[a,d]cyclohepten-5-ones BASF AKTIENGSELLSCHAFT (DE) 1989-07-04 US claimed
EP-0075698-B1 PROCESS FOR THE PREPARATION OF 10,11-DIHYDRO-5H-DIBENZO(A,D) CYCLOHEPTEN-5-ON AND ITS SUBSTITUTION PRODUCTS HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1986-01-02 EP claimed
EP-4632110-A1 PROCESS FOR THE HALOGENATION OF ORGANIC COMPOUNDS ESy-Labs-GmbH (DE) 2025-10-15 EP disclosed
CN-120001297-A Capsule 宝洁公司 2025-05-16 CN disclosed
CN-113660926-B capsule 宝洁公司 2025-03-07 CN disclosed
CN-114007734-B Method for preparing capsules 宝洁公司 2025-01-17 CN disclosed
EP-4426705-A1 CYCLOHEPTA-THIENO-DIAZEPINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE GABA A GAMMA1 RECEPTOR F. Hoffmann-La Roche AG (CH) 2024-09-11 EP disclosed
US-20240294543-A1 CYCLOHEPTA-THIENO-DIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM HOFFMANN-LA ROCHE INC. (US) 2024-09-05 US disclosed
US-12043755-B2 Compositions, methods, and articles relating to in-situ crosslinking of polyamides during additive manufacturing XEROX CORPORATION (US) 2024-07-23 US disclosed
CN-115515957-B Stereoselective synthesis of intermediates for the preparation of heterocyclic compounds 太景生物科技股份有限公司 2024-06-25 CN disclosed
EP-0035711-B1 10-SUBSTITUTED-5-CYANOMETHYLENE-DIBENZO-(A,D)CYCLOHEPTENES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1984-05-09 EP disclosed
US-4438130-A Analgesic 1-oxa-, aza- and thia-spirocyclic compounds THE UPJOHN COMPANY (US) 1984-03-20 US disclosed
US-4420568-A DETERMINING LIGANDS IN SAMPLE ABBOTT LABORATORIES (US) 1983-12-13 US disclosed
EP-0089759-A1 Dibenzocycloheptenylidene compounds for use in modulating the immune response AMERICAN HOME PRODUCTS CORPORATION (US) 1983-09-28 EP disclosed
EP-0075698-A2 Process for the preparation of 10,11-dihydro-5H-dibenzo(a,d) cyclohepten-5-on and its substitution products HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1983-04-06 EP disclosed
EP-0075698-A2 Process for the preparation of 10,11-dihydro-5H-dibenzo(a,d) cyclohepten-5-on and its substitution products HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1983-04-06 EP disclosed
US-4154852-A ANTIDEPRESSANTS ROUSSEL UCLAF (FR) 1979-05-15 US disclosed
US-3919321-A Halo-substituted-5H-dibenzo{8 a,d{9 cyclohepten-5-ones HOFFMANN LA ROCHE 1975-11-11 US disclosed