⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458328 | 0.79 | — | — | |
| SCHEMBL9303806 | 0.74 | — | — | |
| SCHEMBL788280 | 0.67 | — | — | |
| SCHEMBL1533439 | 0.67 | — | — | |
| SCHEMBL6403967 | 0.67 | — | — | |
| SCHEMBL11496566 | 0.67 | — | — | |
| SCHEMBL11636625 | 0.67 | — | — | |
| SCHEMBL170397 | 0.65 | — | — | |
| SCHEMBL10596901 | 0.65 | — | — | |
| SCHEMBL11496567 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738895-B2 | Oligomeric compounds and methods | IONIS PHARMACEUTICALS, INC. (US) | 2017-08-22 | — | — | US | claimed |
| CN-104031086-B | Method for synthesizing alpha-amino alkyl phosphonate compounds | 湖南大学 | 2017-05-10 | — | — | CN | claimed |
| US-20150167006-A1 | OLIGOMERIC COMPOUNDS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2015-06-18 | — | — | US | claimed |
| US-8987435-B2 | Oligomeric compounds and methods | ISIS PHARMACEUTICALS, INC. (US) | 2015-03-24 | — | — | US | claimed |
| CN-104031086-A | Method for synthesizing alpha-amino alkyl phosphonate compounds | UNIV HUNAN | 2014-09-10 | — | — | CN | claimed |
| US-8512976-B2 | Selective growth media | OXOID LIMITED (GB) | 2013-08-20 | — | — | US | claimed |
| EP-2447274-A2 | Oligomeric compounds and methods | Isis Pharmaceuticals, Inc. (US) | 2012-05-02 | — | — | EP | claimed |
| US-20110313019-A1 | OLIGOMERIC COMPOUNDS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2011-12-22 | — | — | US | claimed |
| EP-2358398-A2 | OLIGOMERIC COMPOUNDS AND METHODS | Isis Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | claimed |
| US-20100248331-A1 | SELECTIVE GROWTH MEDIA | DRUGGAN PATRICK | 2010-09-30 | — | — | US | claimed |
| WO-2010048585-A2 | OLIGOMERIC COMPOUNDS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | WO | claimed |
| EP-1334175-B1 | IMPROVEMENTS IN OR RELATING TO SELECTIVE AGENTS FOR BIOLOGICAL CULTURES | OXOID LTD (GB) | 2009-12-23 | — | — | EP | claimed |
| CN-1282653-C | Fluoric alpha-aminoalkyl phosphonate with agricultural antiviral activity and its synthesis | UNIV GUIZHOU (CN) | 2006-11-01 | — | — | CN | claimed |
| CN-1432573-A | Fluoric alpha-aminoalkyl phosphonate with agricultural antiviral activity and its synthesis | UNIV GUIZHOU (CN) | 2003-07-30 | — | — | CN | claimed |
| WO-1995031572-A1 | AMINOHYDROCARBON PHOSPHONATE OLIGONUCLEOTIDES AND USES THEREFOR | PHARMGENICS, INC. (US) | 1995-11-23 | — | — | WO | claimed |
| US-20240229029-A9 | COMPOSITIONS AND METHODS FOR TREATMENT OF FRIEDREICH'S ATAXIA | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240141348-A1 | ALLELE SELECTIVE INHIBITION OF MUTANT C9ORF72 FOCI EXPRESSION BY DUPLEX RNAS TARGETING THE EXPANDED HEXANUCLEOTIDE REPEAT | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-05-02 | — | — | US | disclosed |
| US-4795632-A | ACRYLALDEHYDE-ACRYLIC ACID COPOLYMER AND PHOSPHATE OR PHOSPHONATE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-01-03 | — | — | US | disclosed |
| EP-0253179-A2 | A-acylamino aminoalkyl phophonate angiotensin converting enzyme inhibitors | E.R. Squibb & Sons, Inc. (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4013813-A | AMINOALKYLPHOSPHONIC ACID ESTER-BASED TEXTILE FIRE RETARDANTS | LEBLANC RESEARCH CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |