SCHEMBL458328

SCHEMBL458328

C=CC(N)O[PH](=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458327 0.79
SCHEMBL9303806 0.75
SCHEMBL788277 0.72
SCHEMBL6403970 0.70
SCHEMBL3394983 0.70
SCHEMBL1533440 0.70
SCHEMBL11636629 0.70
SCHEMBL21670459 0.70 LPAR2 (0.31)
SCHEMBL402217 0.69
SCHEMBL10596907 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759518-B1 Bleaching compositions with improved performance and stability and their use MKS DEVO KIMYEVI MAD SAN TIC A S (TR) 2019-05-22 EP claimed
US-9738895-B2 Oligomeric compounds and methods IONIS PHARMACEUTICALS, INC. (US) 2017-08-22 US claimed
US-20150167006-A1 OLIGOMERIC COMPOUNDS AND METHODS ISIS PHARMACEUTICALS, INC. (US) 2015-06-18 US claimed
US-8987435-B2 Oligomeric compounds and methods ISIS PHARMACEUTICALS, INC. (US) 2015-03-24 US claimed
WO-2014114703-A1 BLEACHING COMPOSITIONS WITH IMPROVED PERFORMANCE AND STABILITY MKS-DEVO KIMYEVI MAD. SAN. TIC. A.S. (TR) 2014-07-31 WO claimed
EP-2759518-A1 Bleaching compositions with improved performance and stability MKS-DEVO Kimyevi Mad. San. Tic. A.S. (TR) 2014-07-30 EP claimed
EP-2554742-A1 Stable concentrated hydrogen peroxide compositions for bleaching textiles Sengün, Mehmet Korgün (TR) 2013-02-06 EP claimed
EP-2447274-A2 Oligomeric compounds and methods Isis Pharmaceuticals, Inc. (US) 2012-05-02 EP claimed
US-20110313019-A1 OLIGOMERIC COMPOUNDS AND METHODS ISIS PHARMACEUTICALS, INC. (US) 2011-12-22 US claimed
EP-2358398-A2 OLIGOMERIC COMPOUNDS AND METHODS Isis Pharmaceuticals, Inc. (US) 2011-08-24 EP claimed
WO-2010048585-A2 OLIGOMERIC COMPOUNDS AND METHODS ISIS PHARMACEUTICALS, INC. (US) 2010-04-29 WO claimed
WO-1995031572-A1 AMINOHYDROCARBON PHOSPHONATE OLIGONUCLEOTIDES AND USES THEREFOR PHARMGENICS, INC. (US) 1995-11-23 WO claimed
EP-0608018-A1 Amino alkyl phosphonate as antiwear additive for lubricant containing hydrophylic basestock Akzo Nobel N.V. (NL) 1994-07-27 EP claimed
US-20240229029-A9 COMPOSITIONS AND METHODS FOR TREATMENT OF FRIEDREICH'S ATAXIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-11 US disclosed
US-20240141348-A1 ALLELE SELECTIVE INHIBITION OF MUTANT C9ORF72 FOCI EXPRESSION BY DUPLEX RNAS TARGETING THE EXPANDED HEXANUCLEOTIDE REPEAT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-05-02 US disclosed
US-20240132889-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF FRIEDREICH'S ATAXIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-25 US disclosed
US-4795632-A ACRYLALDEHYDE-ACRYLIC ACID COPOLYMER AND PHOSPHATE OR PHOSPHONATE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-01-03 US disclosed
EP-0253179-A2 A-acylamino aminoalkyl phophonate angiotensin converting enzyme inhibitors E.R. Squibb &amp; Sons, Inc. (US) 1988-01-20 EP disclosed
US-4059716-A TREATING WITH AN AMINE SALT OR QUATERNARY AMMONIUM COMPOUND BASF AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed
US-4013813-A AMINOALKYLPHOSPHONIC ACID ESTER-BASED TEXTILE FIRE RETARDANTS LEBLANC RESEARCH CORPORATION (US) 1977-03-22 US disclosed