Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177576 | 0.84 | MCHR1 (0.43) | NPC1RAB9AMCHR1KCNH2LMNA | |
| SCHEMBL2174848 | 0.81 | MCHR1 (0.43) | NPC1RAB9AMCHR1KCNH2LMNA | |
| SCHEMBL2179048 | 0.79 | TSHR (0.42) | MCHR1KCNH2 | |
| SCHEMBL2177697 | 0.78 | MTNR1A (0.47) | ALDH1A1MTNR1AHTT | |
| SCHEMBL2178414 | 0.77 | TSHR (0.43) | MCHR1KCNH2 | |
| SCHEMBL2175750 | 0.77 | NPC1 (0.46) | NPC1RAB9AMCHR1KCNH2ALDH1A1 | |
| SCHEMBL2177816 | 0.77 | MCHR1 (0.46) | MCHR1ALDH1A1 | |
| SCHEMBL2178661 | 0.76 | MTNR1A (0.48) | ALDH1A1MTNR1A | |
| SCHEMBL2177993 | 0.75 | MCHR1 (0.44) | MCHR1KCNH2 | |
| SCHEMBL2177626 | 0.73 | NPC1 (0.43) | NPC1RAB9ACYP19A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948601-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | Crystalgenomics, Inc. (KR) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007043835-A1 | FAB I INHIBITOR AND PROCESS FOR PREPARING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-04-19 | — | — | WO | disclosed |