SCHEMBL4583405

SCHEMBL4583405

Nc1ccc(-c2cc(C(=O)O)c(N)c(C(=O)O)c2C(=O)O)c(C(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.49
KDM4E B2RXH2 8/20 0.49
MAPT P10636 6/20 0.49
MEN1 O00255 6/20 0.49
THRB P10828 5/20 0.49
ALDH1A1 P00352 5/20 0.49
TDP1 Q9NUW8 4/20 0.49
HSD17B10 Q99714 4/20 0.49
RECQL P46063 3/20 0.49
USP2 O75604 3/20 0.49
MCL1 Q07820 3/20 0.49
CASP7 P55210 3/20 0.49
CYP3A4 P08684 2/20 0.49
PKM P14618 2/20 0.49
POLB P06746 2/20 0.49
ALOX15 P16050 2/20 0.49
CASP1 P29466 2/20 0.49
APEX1 P27695 1/20 0.49
BLM P54132 1/20 0.49
TNF P01375 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713768 0.84 KDM4E (0.65) KMT2AKDM4EMAPTMEN1THRB
Hydrochloric Acid SCHEMBL8956634 0.82 KMT2A (0.69) KMT2AKDM4EMAPTMEN1THRB
Ammonia Solution, Strong SCHEMBL5267316 0.82 KDM4E (0.63) KMT2AKDM4EMAPTMEN1THRB
Water SCHEMBL28033077 0.82 KDM4E (0.63) KMT2AKDM4EMAPTMEN1THRB
SCHEMBL31300453 0.82 KDM4E (0.63) KMT2AKDM4EMAPTMEN1THRB
SCHEMBL15831194 0.74 MEN1 (0.53) KMT2AKDM4EMAPTMEN1THRB
Terephthalamide SCHEMBL17097371 0.74 MAPT (0.53) KMT2AKDM4EMAPTMEN1THRB
SCHEMBL4582858 0.73 HSD17B10 (0.58) KMT2AKDM4EMAPTMEN1THRB
SCHEMBL4583411 0.72 KMT2A (0.51) KMT2AKDM4EMAPTMEN1THRB
SCHEMBL2890556 0.72 FOLH1 (0.57) KMT2AKDM4EMAPTMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7452610-B2 Multi-layer polyimide films and flexible circuit substrates therefrom DU PONT TORAY COMPANY LIMITED (JP) 2008-11-18 US disclosed
EP-1614535-B1 Multi-layer polyimide films and flexible circuit substrates therefrom DUPONT TORAY COMPANY LTD (JP) 2007-10-24 EP disclosed
US-20070003773-A1 Multi-layer polyimide films and flexible circuit substrates therefrom DUPONT TORAY CO. LTD. (JP) 2007-01-04 US disclosed
EP-1616898-A1 Polyamic acids, polyimide films and polyimide-metal laminates and methods for making same DuPont-Toray Company, Ltd. (JP) 2006-01-18 EP disclosed
US-20060009615-A1 Polyamic acids, polyimide films and polymide-metal laminates and methods for making same DUPONT TORAY CO. LTD. (JP) 2006-01-12 US disclosed
EP-1614535-A1 Multi-layer polyimide films and flexible circuit substrates therefrom DuPont-Toray Company, Ltd. (JP) 2006-01-11 EP disclosed