SCHEMBL4582858

SCHEMBL4582858

Nc1ccc(-c2ccc(N)cc2C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.58
KMT2A Q03164 4/20 0.57
KDM4E B2RXH2 4/20 0.57
MAPT P10636 3/20 0.57
MEN1 O00255 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
ALDH1A1 P00352 3/20 0.57
THRB P10828 2/20 0.57
RECQL P46063 2/20 0.57
CYP3A4 P08684 2/20 0.57
MCL1 Q07820 2/20 0.57
USP2 O75604 2/20 0.57
POLB P06746 1/20 0.57
PKM P14618 1/20 0.57
APEX1 P27695 1/20 0.57
BLM P54132 1/20 0.57
TNF P01375 1/20 0.57
HSPD1 P10809 1/20 0.57
CYP2C9 P11712 1/20 0.57
HPGD P15428 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890556 0.90 FOLH1 (0.57) HSD17B10KMT2AKDM4EMAPTMEN1
SCHEMBL14865793 0.89 HSD17B10 (0.51) HSD17B10KMT2AKDM4EMAPTMEN1
SCHEMBL27826819 0.89 EPRS1 (0.58) HSD17B10KMT2AKDM4EMAPTMEN1
SCHEMBL713768 0.87 KDM4E (0.65) HSD17B10KMT2AKDM4EMAPTMEN1
SCHEMBL4584345 0.85 KMT2A (0.70) HSD17B10KMT2AKDM4EMAPTMEN1
Ammonia Solution, Strong SCHEMBL5267316 0.85 KDM4E (0.63) HSD17B10KMT2AKDM4EMAPTMEN1
Hydrochloric Acid SCHEMBL8956634 0.85 KMT2A (0.69) HSD17B10KMT2AKDM4EMAPTMEN1
SCHEMBL31300453 0.85 KDM4E (0.63) HSD17B10KMT2AKDM4EMAPTMEN1
Water SCHEMBL28033077 0.85 KDM4E (0.63) HSD17B10KMT2AKDM4EMAPTMEN1
SCHEMBL3789235 0.84 MAPT (0.50) HSD17B10KMT2AKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7452610-B2 Multi-layer polyimide films and flexible circuit substrates therefrom DU PONT TORAY COMPANY LIMITED (JP) 2008-11-18 US claimed
EP-1614535-B1 Multi-layer polyimide films and flexible circuit substrates therefrom DUPONT TORAY COMPANY LTD (JP) 2007-10-24 EP claimed
US-20070003773-A1 Multi-layer polyimide films and flexible circuit substrates therefrom DUPONT TORAY CO. LTD. (JP) 2007-01-04 US claimed
EP-1616898-A1 Polyamic acids, polyimide films and polyimide-metal laminates and methods for making same DuPont-Toray Company, Ltd. (JP) 2006-01-18 EP claimed
US-20060009615-A1 Polyamic acids, polyimide films and polymide-metal laminates and methods for making same DUPONT TORAY CO. LTD. (JP) 2006-01-12 US claimed
EP-1614535-A1 Multi-layer polyimide films and flexible circuit substrates therefrom DuPont-Toray Company, Ltd. (JP) 2006-01-11 EP claimed
WO-2021029243-A1 COLORED RESIN COMPOSITION, CURED PRODUCT AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
WO-2021028960-A1 COLORED RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
US-20190153225-A1 POLYIMIDE COMPOSITION HAVING A LOW COEFFICIENT OF THERMAL EXPANSION JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2019-05-23 US disclosed
EP-3142777-B1 COMPOSITE POLYAMIDE MEMBRANE POST TREATED WITH NITROUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-24 EP disclosed
EP-3092057-B1 TREATMENT OF AQUEOUS MIXTURES CONTAINING ANIONIC SURFACTANTS USING FOULING RESISTANT REVERSE OSMOSIS MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-19 EP disclosed
EP-3092056-B1 DESALINATION OF AQUEOUS MIXTURE CONTAINING NANO-SIZED PARTICLES USING FOULING RESISTANT REVERSE OSMOSIS MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-01 EP disclosed
EP-3077088-B1 METHOD FOR FORMING A COMPOSITE POLYAMIDE MEMBRANE POST TREATED WITH NITRIOUS ACID DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-27 EP disclosed
EP-1616898-A1 Polyamic acids, polyimide films and polyimide-metal laminates and methods for making same DuPont-Toray Company, Ltd. (JP) 2006-01-18 EP disclosed
US-20060009615-A1 Polyamic acids, polyimide films and polymide-metal laminates and methods for making same DUPONT TORAY CO. LTD. (JP) 2006-01-12 US disclosed
US-20060009615-A1 Polyamic acids, polyimide films and polymide-metal laminates and methods for making same DUPONT TORAY CO. LTD. (JP) 2006-01-12 US disclosed
EP-1614535-A1 Multi-layer polyimide films and flexible circuit substrates therefrom DuPont-Toray Company, Ltd. (JP) 2006-01-11 EP disclosed
EP-1614535-A1 Multi-layer polyimide films and flexible circuit substrates therefrom DuPont-Toray Company, Ltd. (JP) 2006-01-11 EP disclosed
JP-2005054172-A POLYAMIC ACID, POLYIMIDE FILM FORMED OUT OF THE SAME, METHOD FOR PRODUCING THE SAME, AND FLEXIBLE CIRCUIT BOARD DU PONT TORAY CO LTD 2005-03-03 JP disclosed
US-3963796-A DIAMINODIPHENYLMETHANEDICARBOXYLIC ACID HITACHI, LTD. (JA) 1976-06-15 US disclosed