SCHEMBL45835

SCHEMBL45835

Oc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.54
RAB9A P51151 6/20 0.54
LMNA P02545 1/20 0.54
KDM4E B2RXH2 5/20 0.42
HPGD P15428 1/20 0.42
POLB P06746 3/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 4/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX5 P09917 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 2/20 0.39
ESR2 Q92731 1/20 0.38
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
CASP1 P29466 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HSP90AB1 P08238 1/20 0.36
KDM6B O15054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL29031132 0.95 NPC1 (0.50) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL17201891 0.89 NPC1 (0.42) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL28556638 0.86 NPC1 (0.40) NPC1RAB9ALMNAPOLBHSP90AA1
Acrylic Acid SCHEMBL28279573 0.86 NPC1 (0.43) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL30337840 0.85 NPC1 (0.69) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL7857203 0.85 NPC1 (0.69) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL11374684 0.84 ESR2 (0.44) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL11377466 0.81 NPC1 (0.51) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL906023 0.81 NPC1 (0.75) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL5471102 0.81 POLB (0.53) NPC1RAB9ALMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192518-A Thermoplastic polyester elastomer and preparation method and application thereof 金发科技股份有限公司 2025-06-24 CN claimed
CN-120137409-A Flame-retardant and aging-resistant cable for solar power generation and preparation method thereof 成都川缆电缆有限公司 2025-06-13 CN claimed
EP-2794723-B2 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2025-06-04 EP claimed
CN-120005388-A Modified glass fiber reinforced nylon resin composition and preparation method thereof 深圳市精研科洁科技股份有限公司 2025-05-16 CN claimed
CN-120005498-A Weather-resistant scratch-resistant coated glass and preparation method thereof 山东黑山玻璃集团江苏光电科技有限公司 2025-05-16 CN claimed
CN-119431964-B High-foaming low-density composite sealing strip material and preparation method thereof 兴宇汽车零部件股份有限公司 2025-04-25 CN claimed
CN-119820899-A Special polyethylene isolation preservative film for rubber tires and preparation method thereof 昊辰(无锡)塑业有限公司 2025-04-15 CN claimed
CN-119433993-B Flame-retardant finishing method for polyester knitted fabric 安徽金弘润新材料科技有限公司 2025-04-04 CN claimed
CN-119684877-A High-temperature-resistant corrosion-resistant coating and preparation method thereof 信阳中毅高热材料有限公司 2025-03-25 CN claimed
CN-119433993-A Flame-retardant finishing method for polyester knitted fabric 安徽金弘润新材料科技有限公司 2025-02-14 CN claimed
US-20130168617-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-04 US claimed
WO-2013096587-A1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO claimed
WO-2013096604-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO claimed
US-6864325-B2 Metathesis ring-opening polymerization; rigidity, flexible packaging; photostability, heat and oxidation resistance CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-08 US claimed
US-20030191242-A1 Romp with oligomeric uv-absorbers CIBA SPECIALTY CHEMICALS CORP. 2003-10-09 US claimed
EP-1263833-A1 ROMP WITH OLIGOMERIC UV-ABSORBERS Ciba SC Holding AG (CH) 2002-12-11 EP claimed
WO-2001062821-A1 ROMP WITH OLIGOMERIC UV-ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-30 WO claimed
EP-0113150-B1 PROCESS FOR COATING WOOD OR WOOD FIBRES-CONTAINING SUBSTRATES, AND AN OXIDATIVELY DRYING COATING COMPOSITION TO BE USED THEREWITH AKZO N.V. (NL) 1988-04-20 EP claimed
US-4505986-A ALKYD RESIN MODIFIED BY A 2H-BENZOTRIAZOLE OR BENZOPHENONE DERIVATIVE;DURABILITY;WEATHERPROOFING AKZO N.V. (NL) 1985-03-19 US claimed
EP-0113150-A1 Process for coating wood or wood fibres-containing substrates, and an oxidatively drying coating composition to be used therewith AKZO N.V. (NL) 1984-07-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191242-A1 Romp with oligomeric uv-absorbers OSTC, OCIAD1, OCIAD2 NPC1 3453/4885RAB9A 2546/4885LMNA 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.