Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45835 | 0.86 | NPC1 (0.54) | NPC1RAB9ALMNAKDM4EMAPT | |
| Resorcinol SCHEMBL29031132 | 0.82 | NPC1 (0.50) | NPC1RAB9ALMNAKDM4EMAPT | |
| SCHEMBL29384531 | 0.81 | NPC1 (0.41) | NPC1RAB9ALMNAKDM4EMAPT | |
| SCHEMBL16581362 | 0.81 | NPC1 (0.41) | NPC1RAB9ALMNAKDM4EMAPT | |
| SCHEMBL14017586 | 0.80 | NOX1 (0.48) | NPC1RAB9ALMNAKDM4EMAPT | |
| SCHEMBL17201891 | 0.76 | NPC1 (0.42) | NPC1RAB9ALMNATYRKDM4E | |
| SCHEMBL9868391 | 0.76 | NPC1 (0.47) | NPC1RAB9ALMNAKDM4EMAPT | |
| SCHEMBL21630099 | 0.75 | MYC (0.44) | NPC1RAB9ATYRKDM4EMAPT | |
| SCHEMBL29880992 | 0.75 | MYC (0.44) | NPC1RAB9ATYRKDM4EMAPT | |
| SCHEMBL14540265 | 0.75 | NPC1 (0.44) | NPC1RAB9ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415474-A | SILICONE HYDROGELS COMPRISING HIGH LEVELS OF POLYAMIDES | 庄臣及庄臣视力保护公司 | 2019-03-01 | — | — | CN | claimed |