Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583566 | 0.88 | EPHX1 (0.43) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL6525832 | 0.88 | EPHX1 (0.45) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9951257 | 0.87 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1030886 | 0.87 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL2968131 | 0.82 | EPHX1 (0.49) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL4312363 | 0.78 | EPHX1 (0.47) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL3274993 | 0.76 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9951715 | 0.76 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL4314193 | 0.76 | EPHX1 (0.43) | EPHX1TRPM8TRPA1 | |
| SCHEMBL851820 | 0.75 | EPHX1 (0.51) | EPHX1TRPM8TRPA1KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-1958627-A2 | Use of certain menthyl-3-oxocarbonic acid esters as physiological cooling agents | Symrise GmbH & Co. KG (DE) | 2008-08-20 | — | — | EP | disclosed |