Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274993 | 1.00 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL1030886 | 0.85 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL9951257 | 0.85 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL851820 | 0.83 | EPHX1 (0.51) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL25784654 | 0.82 | EPHX1 (0.46) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL28108983 | 0.82 | EPHX1 (0.46) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL23166657 | 0.81 | EPHX1 (0.50) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL5495639 | 0.81 | EPHX1 (0.50) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL8743483 | 0.81 | EPHX1 (0.50) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| Hydrochloric Acid SCHEMBL11492237 | 0.81 | EPHX1 (0.50) | EPHX1TRPM8TRPA1TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165559-A1 | Compounds Having a Physiological Effect | NPPA, CYP11B2, SHBG | EPHX1 871/4885TRPM8 412/4885TRPA1 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.