Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | CCNK | O75909 | 2/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585319 | 0.97 | MCHR1 (0.36) | F10MCHR1ROCK2HDAC1HDAC2 | |
| SCHEMBL4583104 | 0.89 | MCHR1 (0.35) | F10MCHR1HDAC1HDAC2 | |
| SCHEMBL8502212 | 0.87 | F10 (0.45) | F10MCHR1 | |
| SCHEMBL3312693 | 0.87 | F10 (0.45) | F10MCHR1 | |
| SCHEMBL4436523 | 0.84 | F10 (0.36) | F10MCHR1HDAC1HDAC2 | |
| SCHEMBL3313509 | 0.84 | F10 (0.45) | F10MCHR1 | |
| SCHEMBL4584327 | 0.84 | CCNK (0.46) | F10MCHR1CCNKCDK12HDAC8 | |
| SCHEMBL4582426 | 0.84 | CCNK (0.46) | F10MCHR1CCNKCDK12HDAC8 | |
| SCHEMBL8509656 | 0.84 | F10 (0.45) | F10MCHR1 | |
| SCHEMBL4584897 | 0.84 | CCNK (0.46) | F10MCHR1CCNKCDK12HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |