Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583623 | 0.97 | F10 (0.38) | MCHR1F10HDAC1HDAC2ROCK2 | |
| SCHEMBL4583104 | 0.92 | MCHR1 (0.35) | MCHR1F10HDAC1HDAC2TACR1 | |
| SCHEMBL4436523 | 0.86 | F10 (0.36) | MCHR1F10HDAC1HDAC2 | |
| SCHEMBL3313509 | 0.86 | F10 (0.45) | MCHR1F10 | |
| SCHEMBL8509656 | 0.86 | F10 (0.45) | MCHR1F10 | |
| SCHEMBL3312693 | 0.84 | F10 (0.45) | MCHR1F10 | |
| SCHEMBL8502212 | 0.84 | F10 (0.45) | MCHR1F10 | |
| SCHEMBL4583666 | 0.83 | CCNK (0.43) | MCHR1F10 | |
| SCHEMBL4583390 | 0.83 | CCNK (0.43) | MCHR1F10 | |
| SCHEMBL4584030 | 0.83 | CCNK (0.43) | MCHR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |