Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.57 |
| ▸ | TUBB | P07437 | 2/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584256 | 1.00 | APP (0.64) | APPMAPTTUBB1ABCB1TUBB4A | |
| SCHEMBL4584259 | 1.00 | APP (0.64) | APPMAPTTUBB1ABCB1TUBB4A | |
| SCHEMBL1323553 | 0.94 | TTR (0.62) | APPMAPTABCB1TTRALOX5 | |
| SCHEMBL1323574 | 0.94 | TUBB1 (0.65) | APPMAPTTUBB1ABCB1TUBB4A | |
| SCHEMBL1323551 | 0.94 | TTR (0.62) | APPMAPTABCB1TTRALOX5 | |
| SCHEMBL1323569 | 0.94 | TUBB1 (0.65) | APPMAPTTUBB1ABCB1TUBB4A | |
| SCHEMBL1323549 | 0.94 | TTR (0.62) | APPMAPTABCB1TTRALOX5 | |
| SCHEMBL1323565 | 0.94 | TUBB1 (0.65) | APPMAPTTUBB1ABCB1TUBB4A | |
| SCHEMBL1324322 | 0.94 | TTR (0.62) | APPMAPTABCB1TTRALOX5 | |
| SCHEMBL1323567 | 0.94 | TUBB1 (0.65) | APPMAPTTUBB1ABCB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070974-A1 | Alpha, Beta-Unsaturated Sulfones, Sulfoxides, Sulfonimides, Sulfinimides, Acylsulfonamides and Acylsulfinamides and Therapeutic Uses Thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070974-A1 | Alpha, Beta-Unsaturated Sulfones, Sulfoxides, Sulfonimides, Sulfinimides, Acylsulfonamides and Acylsulfinamides and Therapeutic Uses Thereof | DEGS1, SULT1E1, PTDSS1 | APP 121/4885MAPT 1790/4885TUBB1 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.