PTDSS1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL24512537	1.00	20/20
SCHEMBL24512549	1.00	20/20
SCHEMBL24512553	1.00	20/20
SCHEMBL24512558	1.00	20/20
SCHEMBL24512564	1.00	20/20
SCHEMBL24512565	1.00	20/20
SCHEMBL24512569	1.00	20/20
SCHEMBL24512576	1.00	20/20
SCHEMBL24512578	1.00	20/20
SCHEMBL24512580	1.00	20/20
SCHEMBL24512584	1.00	20/20
SCHEMBL24512592	1.00	20/20
SCHEMBL24512597	1.00	20/20
SCHEMBL24512638	1.00	20/20
SCHEMBL24512642	1.00	20/20
SCHEMBL24512645	1.00	20/20
SCHEMBL24512650	1.00	20/20
SCHEMBL24512651	1.00	20/20
SCHEMBL24512653	1.00	20/20
SCHEMBL24512654	1.00	20/20

Clinical trials — most relevant to PTDSS1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
99m Tc-ANNexin-V-128 Scintigraphy for the Identification of Complicated Carotid Atherosclerotic Plaques	PHASE2/PHASE3	WITHDRAWN
Lovaza's Effect on the Activation of Platelets	PHASE2	COMPLETED
The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia	PHASE2	COMPLETED
Hereditary Sensory Neuropathy Serine Trial	PHASE2	UNKNOWN
Phase 2 Study of the Safety of Diannexin in Kidney Transplant Recipients	PHASE2	COMPLETED
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients	PHASE2	COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Efferocytosis and Genomic Polymorphism in Autoimmune Diseases	nan	UNKNOWN
Structural Network on Prostate Cancer in the French Greater West Region	nan	COMPLETED
Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome	nan	COMPLETED
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)	nan	COMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.	nan	UNKNOWN
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia	nan	UNKNOWN
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children	nan	WITHDRAWN
Platelet Changes in Cases of Chronic Iron Over Load	nan	UNKNOWN
Oncometabolome and MALDI-MSI in Upper GI Carcinomas - Chemosensitivity in Esophageal Carcinoma	nan	ACTIVE_NOT_RECRUITING
Sphingo-lipotoxicity and Trans-differentiation of Adipose Tissue in Obesity (SFINGOTRANS)	nan	COMPLETED
Efficacy Study of Vayarin in Children With Autism and Comorbid Attention Deficit Hyperactivity Disorder (ADHD)	nan	COMPLETED
Study of STIM1 Membrane Expression	nan	RECRUITING
P75NTR, Diagnostic Biomarker for Alzheimer's Disease: Quantification Study in Cerebrospinal Fluid	nan	COMPLETED
Vulvodynia: Identification of Potential Relevant Biomarkers	nan	COMPLETED
Epidemiology of Atherosclerosis	nan	COMPLETED
Ceramide Level as Apredictor of Outcomes in Patients of Anterior Myocardial Infarction Undergoing Primary Coronary Intervention	nan	UNKNOWN
Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma	nan	SUSPENDED
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease	nan	COMPLETED
Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans	nan	COMPLETED
Duality of Lipids: the Athlete's Paradox	nan	COMPLETED
Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV	nan	NOT_YET_RECRUITING
Microparticles and the Risk of Re-stenosis Following Balloon Angioplasty in Patients With Peripheral Arterial Disease	nan	WITHDRAWN
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a PTDSS1 binder may also engage these)

Protein	Name	Similarity
Q99LH2	—	1.000	Q99LH2 →
Q5PQL5	—	1.000	Q5PQL5 →
Q00576	—	1.000	Q00576 →
Q5ZM65	—	1.000	Q5ZM65 →
Q2KHY9	—	1.000	Q2KHY9 →
Q803C9	—	0.999	Q803C9 →
B1H3H9	—	0.992	B1H3H9 →
Q0JR55	—	0.986	Q0JR55 →
CDS2	Phosphatidate cytidylyltransferase 2	0.965	landscape →
Q6I628	—	0.964	Q6I628 →
Q99L43	—	0.962	Q99L43 →
F4HXY7	—	0.960	F4HXY7 →
A0JNC1	—	0.958	A0JNC1 →
Q91XU8	—	0.953	Q91XU8 →
P98191	—	0.951	P98191 →
O35052	—	0.949	O35052 →
Q92903	—	0.948	Q92903 →
ACER2	Alkaline ceramidase 2	0.945	landscape →
Q2IBD0	—	0.945	Q2IBD0 →
Q2PG42	—	0.944	Q2PG42 →
Q8R1Z9	—	0.944	Q8R1Z9 →
Q99M96	—	0.943	Q99M96 →
A0M8U1	—	0.943	A0M8U1 →
Q5RBJ7	—	0.943	Q5RBJ7 →
Q8VD53	—	0.943	Q8VD53 →
Q8CIF6	—	0.942	Q8CIF6 →
Q8NBJ9	—	0.942	Q8NBJ9 →
Q9H920	—	0.942	Q9H920 →
Q4VBD2	—	0.941	Q4VBD2 →
Q8BWB6	—	0.941	Q8BWB6 →