Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.51 |
| ▸ | DPP4 | P27487 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462138 | 0.88 | MCHR1 (0.53) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL458155 | 0.85 | PDE4B (0.43) | MCHR1GRIN2BCYP2D6CYP2C9CYP3A4 | |
| SCHEMBL12064536 | 0.80 | MCHR1 (0.49) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL470611 | 0.80 | MCHR1 (0.49) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL470572 | 0.79 | MCHR1 (0.51) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL1724437 | 0.75 | GPR119 (0.44) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL121217 | 0.75 | GPR119 (0.44) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL120100 | 0.75 | GPR119 (0.44) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL121276 | 0.75 | MCHR1 (0.43) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL462728 | 0.74 | MCHR1 (0.44) | MCHR1DPP4KCNH2DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |