SCHEMBL458451

SCHEMBL458451

C=CC[Si](Cl)(C(C)C)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063335 0.78
SCHEMBL5075481 0.74 TSHR (0.33)
SCHEMBL18918479 0.71
SCHEMBL21328513 0.71
SCHEMBL691534 0.71
SCHEMBL6063687 0.69
SCHEMBL6063924 0.69
SCHEMBL6063411 0.69
SCHEMBL116908 0.67
SCHEMBL123281 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11174275-B2 Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use DREXEL UNIVERSITY (US) 2021-11-16 US disclosed
US-20210054003-A1 Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use DREXEL UNIVERSITY 2021-02-25 US disclosed
EP-2614068-A1 ANTHRA[2,3-B:7,6B']DITHIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2013-07-17 EP disclosed
US-20130161568-A1 Anthra[2,3-b:7,6-b']dithiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-27 US disclosed
US-20130161568-A1 Anthra[2,3-b:7,6-b']dithiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-27 US disclosed
US-20130161568-A1 Anthra[2,3-b:7,6-b']dithiophene Derivatives and their Use as Organic Semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-27 US disclosed
WO-2012031659-A1 ANTHRA[2,3-B:7,6B']DITHIOPHENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2012-03-15 WO disclosed
US-20090312559-A1 CATALYTIC ENANTIOSELECTIVE SILYLATIONS OF SUBSTRATES NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT 2009-12-17 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed
US-6797819-B1 Alkaloids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2004-09-28 US disclosed
US-20040014168-A1 Reagents and methods for library synthesis and screening HOWARD HUGHES MEDICAL INSTITUTE 2004-01-22 US disclosed