SCHEMBL5075481

SCHEMBL5075481

C=CCC[Si](Cl)(C(C)C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28890074 0.80 TSHR (0.33) TSHRALDH1A1
SCHEMBL6063881 0.80 TSHR (0.33) TSHRALDH1A1
SCHEMBL715622 0.74
SCHEMBL31097212 0.74 TSHR (0.36) TSHRALDH1A1
SCHEMBL458451 0.74
SCHEMBL6064277 0.72 TSHR (0.35) TSHRALDH1A1
SCHEMBL6063295 0.72 TSHR (0.35) TSHRALDH1A1
SCHEMBL6063929 0.71 TSHR (0.31) TSHR
SCHEMBL28404239 0.71 TSHR (0.39) TSHRALDH1A1
SCHEMBL235358 0.70 TSHR (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
EP-1412392-B1 METALLOCENE CATALYST CONTAINING A CYCLOPENTADIENYL LIGAND SUBSTITUTED BY A SILOXY OR GERMYLOXY GROUP CONTAINING AN OLEFINIC RESIDUE BOREALIS TECH OY (FI) 2008-03-26 EP disclosed
CN-1264868-C Metallocene catalysts containing a cyclopentadienyl ligand substituted by a siloxy or germiloxy group containing an olefinic residue BOREALIS TECH OY (FI) 2006-07-19 CN disclosed
US-7037872-B2 Metallocene catalysts containing a cyclopentadienyl ligand substituted by a siloxy or germiloxy group containing an olefinic residue BOREALIS TECHNOLOGY OY (FI) 2006-05-02 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
CN-1604915-A Metallocene catalysts containing a cyclopentadienyl ligand substituted by a siloxy or germiloxy group containing an olefinic residue BOREALIS TECH OY (FI) 2005-04-06 CN disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed
US-20040198590-A1 Metallocene catalysts containing a cyclopentadienyl ligand substituted by a siloxy or germiloxy group containing an olefinic residue BOREALIS TECHNOLOGY OY (FI) 2004-10-07 US disclosed
EP-1412392-A1 METALLOCENE CATALYST CONTAINING A CYCLOPENTADIENYL LIGAND SUBSTITUTED BY A SILOXY OR GERMYLOXY GROUP CONTAINING AN OLEFINIC RESIDUE Borealis Technology Oy (FI) 2004-04-28 EP disclosed
WO-2003010208-A1 METALLOCENE CATALYSTS CONTAINING A CYCLOPENTADIENYL LIGAND SUBSTITUTED BY A SILOXY OR GERMILOXY GROUP CONTAINING AN OLEFINIC RESIDUE BOREALIS TECHNOLOGY OY (FI) 2003-02-06 WO disclosed