Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.51 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017656 | 0.88 | MEN1 (0.51) | PAK1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL4024310 | 0.85 | MEN1 (0.62) | PAK1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL4018789 | 0.84 | DRD2 (0.44) | PAK1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL4020867 | 0.84 | CYP1A2 (0.55) | MCHR1CRHR1PAK1CYP1A2 | |
| SCHEMBL4020834 | 0.83 | PAK1 (0.60) | PAK1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL4582680 | 0.83 | MEN1 (0.49) | PAK1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL4583304 | 0.83 | CNR1 (0.53) | PAK1MEN1KMT2AHMOX1CYP1A2 | |
| SCHEMBL4016096 | 0.83 | MEN1 (0.49) | MCHR1PAK1MEN1KMT2ADRD2 | |
| SCHEMBL4019718 | 0.83 | CNR1 (0.47) | PAK1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL4023469 | 0.83 | DRD2 (0.44) | MCHR1PAK1MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903038-A1 | N-(1-hetaryl-piperidin-4-yl)-(het)arylamide as EP2 receptor modulators | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-26 | — | — | EP | claimed |
| EP-1903038-A1 | N-(1-hetaryl-piperidin-4-yl)-(het)arylamide as EP2 receptor modulators | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-26 | — | — | EP | disclosed |