Ethylene

Ethylene

SCHEMBL4584731

C=C.N.N.O=C(O)c1c(F)c(F)c(F)c(F)c1F.O=C(O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MEN1 O00255 7/20 0.38
KMT2A Q03164 7/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
GAA P10253 1/20 0.37
HTT P42858 2/20 0.36
PKM P14618 1/20 0.35
MAPK1 P28482 2/20 0.34
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ASPH Q12797 1/20 0.32
KDM8 Q8N371 1/20 0.32
GFER P55789 1/20 0.32
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11055563 0.94 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL20291864 0.94 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
SCHEMBL203915 0.91 CES2 (0.43) CES2CES1MEN1KMT2ASMN1; SMN2
SCHEMBL2150002 0.88 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL10455117 0.88 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL11033629 0.88 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
SCHEMBL16756190 0.88 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
SCHEMBL28389339 0.88 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
SCHEMBL336420 0.88 CES2 (0.42) CES2CES1MEN1KMT2ASMN1; SMN2
Formaldehyde SCHEMBL28740243 0.88 MEN1 (0.36) CES2CES1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530269-B2 Manufacture of a polymer device CAMBRIDGE ENTERPRISE LTD (GB) 2013-09-10 US disclosed
EP-1631995-B1 MANUFACTURE OF A POLYMER DEVICE CAMBRIDGE ENTPR LTD (GB) 2008-07-16 EP disclosed
US-20070172978-A1 Manufacture of a polymer device CAMBRIDGE UNIVERSITY TECHNICAL SERVICE LIMITED (GB) 2007-07-26 US disclosed