SCHEMBL4585292

SCHEMBL4585292

CCCCCCCCCCCCCCCCCCC(C)(CCCCCCCCCCCCCCCCCC)C(N)(O)O

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FDPS P14324 10/20 0.47
SMPD1 P17405 4/20 0.47
GGPS1 O95749 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31149403 1.00 FDPS (0.47) FDPSSMPD1GGPS1
Hydrochloric Acid SCHEMBL28559435 0.84 FDPS (0.45) FDPSSMPD1GGPS1
Hydrochloric Acid SCHEMBL28969844 0.84 FDPS (0.45) FDPSSMPD1GGPS1
Hydrochloric Acid SCHEMBL28980692 0.82 FDPS (0.44) FDPSSMPD1GGPS1
SCHEMBL19201137 0.80 FDPS (0.46) FDPSSMPD1GGPS1
SCHEMBL6938402 0.80 FDPS (0.50) FDPSSMPD1GGPS1
SCHEMBL4141311 0.80 FDPS (0.50) FDPSSMPD1GGPS1
SCHEMBL22799931 0.80 FDPS (0.46) FDPSSMPD1GGPS1
SCHEMBL4286298 0.80 FDPS (0.50) FDPSSMPD1GGPS1
SCHEMBL9205361 0.80 FDPS (0.50) FDPSSMPD1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108472246-A Colloidal solid for being used in drug 剑桥生物制药专利有限公司 2018-08-31 CN claimed
EP-1603535-A4 AROMATASE INHIBITOR DIAGNOSIS AND THERAPY ETHICON INC (US) 2008-10-15 EP disclosed
EP-1616182-A4 ENZYME REPLACEMENT THERAPY WITH 17-BETA-HYDROXYSTEROID DEHYDROGENASE-TYPE 2 ETHICON INC (US) 2008-04-16 EP disclosed
EP-1616182-A2 ENZYME REPLACEMENT THERAPY WITH 17-BETA-HYDROXYSTEROID DEHYDROGENASE-TYPE 2 ETHICON, INC. (US) 2006-01-18 EP disclosed
EP-1603535-A2 AROMATASE INHIBITOR DIAGNOSIS AND THERAPY ETHICON, INC. (US) 2005-12-14 EP disclosed
WO-2004082627-A2 ENZYME REPLACEMENT THERAPY WITH 17-β-HYDROXYSTEROID DEHYDROGENASE-TYPE 2 ETHICON, INC. (US) 2004-09-30 WO disclosed
WO-2004082626-A2 AROMATASE INHIBITOR DIAGNOSIS AND THERAPY ETHICON, INC. (US) 2004-09-30 WO disclosed