Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA7 | P43166 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098421 | 0.79 | — | — | |
| SCHEMBL4585366 | 0.79 | TSHR (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL7096767 | 0.79 | TSHR (0.34) | TSHR | |
| SCHEMBL7096981 | 0.78 | SMN1; SMN2 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7096505 | 0.76 | LMNA (0.35) | TSHR | |
| SCHEMBL6247104 | 0.74 | ALDH1A1 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9806067 | 0.74 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL15210417 | 0.74 | — | — | |
| SCHEMBL7097254 | 0.73 | MAPT (0.42) | TSHRCA1CA2 | |
| SCHEMBL7096884 | 0.73 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |