Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255523 | 0.87 | ALDH1A1 (0.65) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL11580414 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL7675499 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL2385885 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL7185506 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL1984327 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL30417552 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10583241 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10172753 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL3231685 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841761-A4 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2008-10-29 | — | — | EP | disclosed |
| EP-1841761-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006080591-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2006-08-03 | — | — | WO | disclosed |