Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.54 |
| ▸ | CHRND | Q07001 | 5/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.54 |
| ▸ | CHRNG | P07510 | 1/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372487 | 0.87 | CHRND (0.59) | FOLH1LMNAGRIA1CHRNDCHRNA1 | |
| SCHEMBL8975007 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL28031750 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL620470 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL38651117 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL23778217 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL6121330 | 0.84 | LMNA (0.74) | LMNANAALAD2EPHX2KMT2A | |
| SCHEMBL28663068 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL28379862 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 | |
| SCHEMBL7142929 | 0.84 | GRIA1 (0.50) | FOLH1NAALAD2GRIA1CHRNDCHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113992-A2 | GEL COMPOSITIONS COMPRISING UREA DERIVATIVES | PLIVA HRVATSKA D.O.O. (HR) | 2008-09-25 | — | — | WO | claimed |
| WO-2008113992-A2 | GEL COMPOSITIONS COMPRISING UREA DERIVATIVES | PLIVA HRVATSKA D.O.O. (HR) | 2008-09-25 | — | — | WO | disclosed |