Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585915 | 1.00 | IGF1R (0.44) | IGF1RALDH1A1NPSR1CYP19A1NPC1 | |
| SCHEMBL4583973 | 0.84 | MEN1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4583968 | 0.84 | MEN1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6618598 | 0.83 | MEN1 (0.48) | ALDH1A1NPC1CRHBPCRHR2MC4R | |
| SCHEMBL6618592 | 0.83 | MEN1 (0.48) | ALDH1A1NPC1CRHBPCRHR2MC4R | |
| SCHEMBL1989446 | 0.83 | ALDH1A1 (0.49) | ALDH1A1NPC1CRHBPCRHR2MC4R | |
| SCHEMBL1680543 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1CRHBPCRHR2MAPT | |
| SCHEMBL4584829 | 0.78 | MEN1 (0.48) | ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL4584835 | 0.78 | MEN1 (0.48) | ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL19245780 | 0.75 | CA12 (0.47) | ALDH1A1CRHBPCRHR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |