P-Nitrophenol

P-Nitrophenol

SCHEMBL4586026

CCCCCC(=O)O.O=[N+]([O-])c1ccc(O)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
MAPT P10636 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 1/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B3 P37058 6/20 0.50
AKR1B1 P15121 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
PPARG P37231 5/20 0.48
PPARD Q03181 5/20 0.48
PPARA Q07869 5/20 0.48
HDAC11 Q96DB2 4/20 0.48
TSHR P16473 3/20 0.48
GPR84 Q9NQS5 3/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Nitrophenol SCHEMBL8388584 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
Myristic Acid SCHEMBL28187818 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
Palmitic Acid SCHEMBL911132 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
Dodecanoate SCHEMBL9346242 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
Octanoic Acid SCHEMBL4602551 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
Stearic Acid SCHEMBL27576390 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
Decanoic Acid SCHEMBL28355377 0.98 ALDH1A1 (0.59) ALDH1A1KMT2AHSD17B3PPARGPPARD
P-Nitrophenol SCHEMBL15253930 0.95 ALDH1A1 (0.52) ALDH1A1MAPTKMT2ALMNACRHBP
Palmitic Acid SCHEMBL28923726 0.93 ALDH1A1 (0.54) ALDH1A1MAPTKMT2ALMNACRHBP
Dodecanoate SCHEMBL27633293 0.92 ALDH1A1 (0.61) ALDH1A1MAPTKMT2AAKR1B1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119286820-A Novel esterase and encoding gene and novel application thereof 常州大学 2025-01-10 CN claimed
CN-111139229-B Novel GDSL family lipid hydrolase EII-2 and encoding gene and application thereof 自然资源部第二海洋研究所 2023-05-16 CN claimed
CN-111019921-B High-tolerance lipid hydrolase E93 and encoding gene and application thereof 自然资源部第二海洋研究所 2023-04-28 CN claimed
CN-111057691-B Novel GDSL family lipid hydrolase EII-3 and encoding gene and application thereof 自然资源部第二海洋研究所 2023-04-28 CN claimed
CN-107189955-B Novel deep-sea thermostable alkaline esterase and application thereof 自然资源部第二海洋研究所 2022-07-15 CN claimed
CN-110004125-B Novel alkali-resistant and organic solvent-resistant esterase from marine bacteria and application thereof 自然资源部第二海洋研究所 2022-05-20 CN claimed
CN-113444711-A Preparation method of peptide assembled hydrolytic enzyme with substrate selectivity 天津大学 2021-09-28 CN claimed
CN-109971734-B PH-insensitive high-temperature-tolerant HSL family lipid hydrolase and application thereof 杭州浦泰生物科技有限公司 2021-04-13 CN claimed
CN-109943550-B Marine bacterium-derived esterase Erp3, and coding gene and application thereof 自然资源部第二海洋研究所 2021-01-26 CN claimed
CN-108504618-B Recombinant bacterium for expressing lipase with R configuration selectivity and application thereof 华南理工大学 2020-08-18 CN claimed
CN-107893060-B Thermostable salt-tolerant SGNH family hydrolase derived from marine bacteria and application thereof 自然资源部第二海洋研究所 2020-05-05 CN claimed
CN-119736273-A Esterase and application thereof in plastic degradation 山东大学 2025-04-01 CN disclosed
CN-119410606-A Lipase mutant and preparation method and application thereof 湖北大学 2025-02-11 CN disclosed
CN-119286820-A Novel esterase and encoding gene and novel application thereof 常州大学 2025-01-10 CN disclosed
CN-118480529-A Lipase Lip1897-H106Y, coding gene thereof and application thereof in preparation of DHAPG 中国海洋大学 2024-08-13 CN disclosed
CN-105062989-A Deep-sea sediment resource esterase EST2 as well as coding gene and application thereof SECOND INST OCEANOGRAPHY SOA 2015-11-18 CN disclosed
EP-1694837-A4 METHOD AGENCY SCIENCE TECH & RES (SG) 2008-07-23 EP disclosed
US-20070207463-A1 Method LIU ZIDUO 2007-09-06 US disclosed
EP-1694837-A1 METHOD Agency for Science, Technology and Research (SG) 2006-08-30 EP disclosed
WO-2005049831-A1 METHOD AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH (SG) 2005-06-02 WO disclosed