Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622136 | 0.92 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7665196 | 0.90 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL6951608 | 0.90 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL8622977 | 0.90 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL8684827 | 0.83 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL8621779 | 0.83 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL7531520 | 0.82 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL8624489 | 0.82 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL8624513 | 0.82 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL8627924 | 0.81 | EDNRA (0.59) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915699-A4 | STEREOSELECTIVE SYNTHESIS OF ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-0915699-A1 | STEREOSELECTIVE SYNTHESIS OF ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997017071-A1 | STEREOSELECTIVE SYNTHESIS OF ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |