Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 5/20 | 1.00 |
| ▸ | GMPS | P49915 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30946707 | 1.00 | EGFR (1.00) | EGFRERBB2GMPSHDAC6ERBB4 | |
| SCHEMBL12494972 | 0.90 | EGFR (0.81) | EGFRERBB2HDAC6ERBB4AURKB | |
| SCHEMBL4586538 | 0.88 | EGFR (1.00) | EGFRERBB2GMPSHDAC6ERBB4 | |
| SCHEMBL12700568 | 0.85 | EGFR (0.74) | EGFRERBB2HDAC6ERBB4AURKB | |
| SCHEMBL4587635 | 0.85 | EGFR (0.74) | EGFRERBB2HDAC6ERBB4 | |
| SCHEMBL12700472 | 0.85 | EGFR (0.77) | EGFRERBB2HDAC6ERBB4AURKB | |
| SCHEMBL3240208 | 0.84 | EGFR (1.00) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL8104687 | 0.83 | EGFR (0.70) | EGFRERBB2GMPSHDAC6ERBB4 | |
| SCHEMBL3248333 | 0.82 | EGFR (0.80) | EGFRERBB2ERBB4 | |
| SCHEMBL3248334 | 0.82 | EGFR (0.80) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240309327-A1 | CARDIOMYOCYTE PRODUCTION METHOD | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-19 | — | — | US | disclosed |
| EP-4424819-A1 | METHOD FOR PRODUCING MYOCARDIAL CELL LAYER, MYOCARDIAL CELL LAYER, AND USE THEREOF | FUJIFILM Corporation (JP) | 2024-09-04 | — | — | EP | disclosed |
| US-20240277899-A1 | PRODUCTION METHOD OF MYOCARDIAL CELL LAYER, MYOCARDIAL CELL LAYER, AND USE THEREOF | FUJIFILM CORPORATION (JP) | 2024-08-22 | — | — | US | disclosed |
| CN-118159647-A | Method for producing cardiomyocyte layer, and use thereof | 富士胶片株式会社 | 2024-06-07 | — | — | CN | disclosed |
| EP-3431584-B1 | METHODS FOR FREEZING AN AGGREGATE OF PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES | UNIV KYOTO (JP) | 2023-06-28 | — | — | EP | disclosed |
| WO-2023074783-A1 | METHOD FOR PRODUCING MYOCARDIAL CELL LAYER, MYOCARDIAL CELL LAYER, AND USE THEREOF | 富士フイルム株式会社 | 2023-05-04 | — | — | WO | disclosed |
| WO-2023286772-A1 | CARDIOMYOCYTE PRODUCTION METHOD | 三菱ケミカル株式会社 | 2023-01-19 | — | — | WO | disclosed |
| WO-2019175332-A1 | BH4 PATHWAY INHIBITION AND USE THEREOF FOR TREATING T-CELL MEDIATED AUTOIMMUNE DISEASES OR HYPERSENSITIVITY | IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) | 2019-09-19 | — | — | WO | disclosed |
| EP-3150705-B1 | METHOD FOR INDUCING MYOCARDIAL DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING LOW-MOLECULAR COMPOUND | UNIV KYOTO (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-2966166-B1 | PROMOTER OF DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO MYOCARDIUM, WHICH COMPRISES EGF RECEPTOR INHIBITOR | UNIV KYOTO (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-20140309246-A1 | METHODS AND USE OF BIFUNCTIONAL ENZYME-BUILDING CLAMP-SHAPED MOLECULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-10-16 | — | — | US | disclosed |
| EP-2685980-A1 | METHODS AND USE OF BIFUNCTIONAL ENZYME-BUILDING CLAMP-SHAPED MOLECULES | The Trustees Of The University Of Pennsylvania (US) | 2014-01-22 | — | — | EP | disclosed |
| US-8461166-B2 | Anilinoquinazolinyl amide derivatives; radiolabels as bioprobes for Positron Emission Tomography and Single Photon Emission Computed Tomography, and as radiopharmaceuticals for radiotherapy; improved solubility, bioavailability, biostability | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2013-06-11 | — | — | US | disclosed |
| WO-2012125913-A1 | METHODS AND USE OF BIFUNCTIONAL ENZYME-BUILDING CLAMP-SHAPED MOLECULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012125913-A1 | METHODS AND USE OF BIFUNCTIONAL ENZYME-BUILDING CLAMP-SHAPED MOLECULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-09-20 | — | — | WO | disclosed |
| EP-1594504-A4 | NOVEL IRREVERSIBLE INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE AND USES THEREOF FOR THERAPY AND DIAGNOSIS | T K SIGNAL LTD (IL) | 2008-12-17 | — | — | EP | disclosed |
| WO-2006085330-A2 | USE OF PROTEIN TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF LEIOMYOMAS | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2006-08-17 | — | — | WO | disclosed |
| US-20060025430-A1 | Novel irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and uses thereof for therapy and diagnosis | T.K. SIGNAL LTD. (IL) | 2006-02-02 | — | — | US | disclosed |
| EP-1594504-A2 | NOVEL IRREVERSIBLE INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE AND USES THEREOF FOR THERAPY AND DIAGNOSIS | T.K. Signal Ltd. (IL) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004064718-A2 | IRREVERSIBLE INHIBITORS OF EGF RECEPTOR TYROSINE KINASES AND USES THEREOF | T.K. SIGNAL LTD. (IL) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309246-A1 | METHODS AND USE OF BIFUNCTIONAL ENZYME-BUILDING CLAMP-SHAPED MOLECULES | EGFR, JMJD7, ERBB2 | EGFR 1/4885ERBB2 3/4885GMPS 2071/4885 |
| US-20240277899-A1 | PRODUCTION METHOD OF MYOCARDIAL CELL LAYER, MYOCARDIAL CELL LAYER, AND USE THEREOF | KIT, MYLK2, TNNT2 | EGFR 2160/4885ERBB2 2159/4885GMPS 2089/4885 |
| US-20060025430-A1 | Novel irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and uses thereof for therapy and diagnosis | EGFR, ERBB2, ERBB3 | EGFR 1/4885ERBB2 2/4885GMPS 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.