Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4587619 | 0.99 | MEN1 (0.63) | MEN1KMT2AGAAFOXO1HPGD | |
| Hydrochloric Acid SCHEMBL27763903 | 0.88 | KMT2A (0.59) | MEN1KMT2AGAAFOXO1HPGD | |
| Hydrochloric Acid SCHEMBL4588096 | 0.86 | MEN1 (0.48) | MEN1KMT2AGAAFOXO1HPGD | |
| SCHEMBL261670 | 0.84 | MEN1 (0.61) | MEN1KMT2AGAAFOXO1HPGD | |
| Hydrochloric Acid SCHEMBL261938 | 0.83 | MEN1 (0.60) | MEN1KMT2AGAAFOXO1HPGD | |
| SCHEMBL4110428 | 0.83 | MEN1 (0.79) | MEN1KMT2AGAAFOXO1HPGD | |
| SCHEMBL1243866 | 0.82 | KMT2A (0.81) | MEN1KMT2AGAAFOXO1HPGD | |
| Hydrochloric Acid SCHEMBL27763904 | 0.81 | MEN1 (0.60) | MEN1KMT2AGAAFOXO1HPGD | |
| SCHEMBL4587943 | 0.81 | MEN1 (0.45) | MEN1KMT2AGAAFOXO1HPGD | |
| Oxalic Acid SCHEMBL4588543 | 0.80 | MEN1 (0.43) | MEN1KMT2AGAAFOXO1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995240-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |