Styrene

Styrene

SCHEMBL4586301

C=CC=C.C=CCC.C=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
TSHR P16473 1/20 0.64
TP53 P04637 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HDAC8 Q9BY41 2/20 0.38
RELA Q04206 1/20 0.35
CHRNA7 P36544 2/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
MAOB P27338 1/20 0.33
CYP2A6 P11509 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4603330 1.00 ALDH1A1 (0.64) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL5912908 0.95 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL27509238 0.95 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL2233731 0.95 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL8848519 0.95 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL11063484 0.93 ALDH1A1 (0.67) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL7165268 0.93 ALDH1A1 (0.67) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL480124 0.93 ALDH1A1 (0.67) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL27441172 0.91 ALDH1A1 (0.64) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL9614429 0.86 ALDH1A1 (0.64) ALDH1A1TSHRTP53TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474476-B1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME SOLVAY ENGINEERED POLYMERS INC (US) 2005-12-14 EP claimed
EP-1474476-A4 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME SOLVAY ENGINEERED POLYMERS (US) 2005-03-23 EP claimed
EP-1474476-A1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME Solvay Engineered Polymers (US) 2004-11-10 EP claimed
WO-2003068858-A1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME SOLVAY ENGINEERED POLYMERS (US) 2003-08-21 WO claimed
US-6509416-B2 Blend of propylene-hydrophilic monomer metal salt and ethylene-hydrophilic monomer metal salt; enhanced scratch resistance, rigidity, and toughness. SOLVAY ENGINEERED POLYMERS 2003-01-21 US claimed
US-20020107329-A1 Engineered polyolefin materials with enhanced surface durability and methods of making same SOLVAY ENGINEERED POLYMERS, INC. 2002-08-08 US claimed
EP-1554341-A4 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY SOLVAY (BE) 2008-10-01 EP disclosed
EP-1639022-A4 IONOMERIC NANOCOMPOSITES AND ARTICLES THEREFROM SOLVAY (BE) 2006-07-26 EP disclosed
EP-1639022-A2 IONOMERIC NANOCOMPOSITES AND ARTICLES THEREFROM SOLVAY (Société Anonyme) (BE) 2006-03-29 EP disclosed
EP-1474476-B1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME SOLVAY ENGINEERED POLYMERS INC (US) 2005-12-14 EP disclosed
EP-1554341-A1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY Solvay Engineered Polymers (US) 2005-07-20 EP disclosed
US-6914094-B2 Engineered polyolefin materials with enhanced surface durability SOLVAY ENGINEERED POLYMERS, INC. (US) 2005-07-05 US disclosed
EP-1474476-A4 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME SOLVAY ENGINEERED POLYMERS (US) 2005-03-23 EP disclosed
WO-2004035678-A1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY SOLVAY ENGINEERED POLYMERS (US) 2004-04-29 WO disclosed
US-20040072949-A1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY SOLVAY ENGINEERED POLYMERS, INC. 2004-04-15 US disclosed
US-20030207984-A1 Comprises metal salt for neutralization and decreasing opacity; increased scratch and mar resistance while still retaining clarity and thermal stability; thermoforming SOLVAY ENGINEERED POLYMERS, INC. 2003-11-06 US disclosed
US-20030204019-A1 Engineered polyolefin materials with enhanced surface durability SOLVAY ENGINEERED POLYMERS, INC. 2003-10-30 US disclosed
WO-2003068858-A1 ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME SOLVAY ENGINEERED POLYMERS (US) 2003-08-21 WO disclosed
US-6509416-B2 Blend of propylene-hydrophilic monomer metal salt and ethylene-hydrophilic monomer metal salt; enhanced scratch resistance, rigidity, and toughness. SOLVAY ENGINEERED POLYMERS 2003-01-21 US disclosed
US-20020107329-A1 Engineered polyolefin materials with enhanced surface durability and methods of making same SOLVAY ENGINEERED POLYMERS, INC. 2002-08-08 US disclosed