Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 10/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574076 | 1.00 | SLC2A1 (0.40) | SLC2A1DHFRCDK1CCNB1CCNA2 | |
| SCHEMBL4527100 | 0.85 | SLC2A1 (0.36) | SLC2A1DHFR | |
| SCHEMBL823652 | 0.81 | CDK1 (0.40) | SLC2A1DHFRCDK1CCNB1CCNA2 | |
| SCHEMBL4574072 | 0.80 | DHFR (0.47) | SLC2A1DHFRCDK1CCNB1CCNA2 | |
| SCHEMBL4586307 | 0.80 | DHFR (0.47) | SLC2A1DHFRCDK1CCNB1CCNA2 | |
| SCHEMBL823646 | 0.79 | SMN1; SMN2 (0.39) | SLC2A1DHFR | |
| SCHEMBL3605191 | 0.78 | DHFR (0.35) | SLC2A1DHFR | |
| SCHEMBL3609932 | 0.78 | DHFR (0.35) | SLC2A1DHFR | |
| SCHEMBL3598713 | 0.77 | CYP1A2 (0.35) | — | |
| SCHEMBL3607975 | 0.77 | CYP1A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077650-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |