Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711507 | 0.85 | TSHR (0.57) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL23732772 | 0.79 | TSHR (0.60) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL4586560 | 0.79 | TSHR (0.50) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL18307754 | 0.79 | POLB (0.51) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL10832549 | 0.78 | TSHR (0.58) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL18307755 | 0.78 | TSHR (0.63) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL13596714 | 0.77 | TSHR (0.57) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL11303293 | 0.75 | TSHR (0.55) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL13537701 | 0.74 | TSHR (0.53) | TSHRCETPALDH1A1KDM4EFOLH1 | |
| SCHEMBL17357035 | 0.74 | TSHR (0.53) | TSHRCETPALDH1A1KDM4EFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385988-A4 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | SEMOREX INC. | 2004-06-24 | — | — | US | disclosed |
| EP-1385988-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | Semorex Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083708-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | CD2BP2, HAVCR2, EPCAM | TSHR 394/4885CETP 1400/4885ALDH1A1 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.