Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | CETP | P11597 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302597 | 0.85 | ELANE (0.51) | TSHRFOLH1CETPELANEALDH1A1 | |
| SCHEMBL31308128 | 0.84 | LMNA (0.51) | TSHRFOLH1CETPELANEALDH1A1 | |
| SCHEMBL10832549 | 0.82 | TSHR (0.58) | TSHRFOLH1CETPELANEALDH1A1 | |
| SCHEMBL13711507 | 0.82 | TSHR (0.57) | TSHRFOLH1CETPELANEALDH1A1 | |
| SCHEMBL31549517 | 0.81 | TSHR (0.53) | TSHRFOLH1CETPELANEALDH1A1 | |
| SCHEMBL23732772 | 0.80 | TSHR (0.60) | TSHRFOLH1CETPELANEALDH1A1 | |
| SCHEMBL10832425 | 0.78 | TSHR (0.62) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL7376215 | 0.78 | TSHR (0.53) | TSHRFOLH1CETPSLC1A1SLC1A3 | |
| SCHEMBL7376210 | 0.78 | TSHR (0.53) | TSHRFOLH1CETPSLC1A1SLC1A3 | |
| SCHEMBL11310007 | 0.78 | POLB (0.50) | TSHRFOLH1CETPALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451970-A | N-substituted indole derivatives and conjugates thereof for the treatment of cancer | 埃维克斯塔生物公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-0000833-B1 | DERIVATIVES OF PHOSPHONOACYL PROLINES AND THEIR PHARMACEUTICAL USE | E.R. Squibb & Sons, Inc. (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4151172-A | Phosphonoacyl prolines and related compounds | E. R. SQUIBB & SONS, INC. (US) | 1979-04-24 | — | — | US | disclosed |
| EP-0000833-A1 | Derivatives of phosphonoacyl prolines and their pharmaceutical use | E.R. Squibb & Sons, Inc. (US) | 1979-02-21 | — | — | EP | disclosed |