Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531391 | 0.96 | PSMD10 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL6849019 | 0.95 | PSMD10 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL6849012 | 0.95 | PSMD10 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL5854898 | 0.92 | PSMD10 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL2244715 | 0.92 | PSMD10 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL4588419 | 0.92 | PSMD10 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL6853749 | 0.89 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL6852562 | 0.89 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL2348771 | 0.86 | PSMD10 (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 | |
| SCHEMBL3343193 | 0.85 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375098-B2 | 8β-vinyl-11β-(ω-substituted)alkyl-estra-1,3,5(10)-trienes | SCHERING A.G. (DE) | 2008-05-20 | — | — | US | disclosed |
| US-20050065135-A1 | 8beta-Vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065135-A1 | 8beta-Vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes | CYP19A1, HSD17B11, ESR2 | ALDH1A1 474/4885CYP3A4 162/4885CYP2C9 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.