Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178850 | 0.91 | CHRM1 (0.52) | CARM1PRMT6CCNT1CHRM1CHRM3 | |
| SCHEMBL64031 | 0.89 | CARM1 (0.63) | CARM1PRMT6MAPTALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21879607 | 0.87 | CARM1 (0.62) | CARM1PRMT6MAPTALOX12ALDH1A1 | |
| SCHEMBL9667976 | 0.85 | POLB (0.62) | CARM1PRMT6MAPTALOX12ALDH1A1 | |
| SCHEMBL29577342 | 0.81 | CARM1 (0.56) | CARM1PRMT6CCNT1MAPTALOX12 | |
| SCHEMBL375076 | 0.81 | CARM1 (0.56) | CARM1PRMT6MAPTALOX12ALDH1A1 | |
| SCHEMBL22725140 | 0.81 | GRIN2B (0.50) | CARM1PRMT6CHRM3ALDH1A1POLB | |
| SCHEMBL12817956 | 0.81 | CARM1 (0.56) | CARM1PRMT6ALDH1A1HTR6POLB | |
| SCHEMBL3359770 | 0.80 | POLB (0.69) | ALOX12POLBACHEBACE1MEN1 | |
| SCHEMBL5179993 | 0.80 | CARM1 (0.57) | CARM1PRMT6ALDH1A1SLC6A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |