SCHEMBL29577342

SCHEMBL29577342

NC1CCC(NCc2cccc(Cl)c2)CC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.56
PRMT6 Q96LA8 2/20 0.56
CCNT1 O60563 1/20 0.49
MAPT P10636 1/20 0.47
ALOX12 P18054 1/20 0.47
ALDH1A1 P00352 1/20 0.46
POLB P06746 2/20 0.45
CHRM2 P08172 1/20 0.45
PNMT P11086 1/20 0.44
ACHE P22303 4/20 0.44
BACE1 P56817 4/20 0.44
FLT3 P36888 1/20 0.44
BCHE P06276 3/20 0.43
EPHX2 P34913 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TACR1 P25103 1/20 0.43
CCNE1 P24864 2/20 0.43
CDK2 P24941 2/20 0.43
TAAR1 Q96RJ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64031 0.92 CARM1 (0.63) CARM1PRMT6MAPTALOX12ALDH1A1
Hydrochloric Acid SCHEMBL21879607 0.90 CARM1 (0.62) CARM1PRMT6MAPTALOX12ALDH1A1
SCHEMBL9667976 0.85 POLB (0.62) CARM1PRMT6MAPTALOX12ALDH1A1
Formic Acid SCHEMBL5071436 0.83 CARM1 (0.55) CARM1PRMT6MAPTALOX12ALDH1A1
SCHEMBL4586847 0.81 CARM1 (0.56) CARM1PRMT6CCNT1MAPTALOX12
SCHEMBL375076 0.81 CARM1 (0.56) CARM1PRMT6MAPTALOX12ALDH1A1
SCHEMBL15587414 0.81 ACHE (0.60) CARM1PRMT6ALDH1A1POLBACHE
SCHEMBL5694934 0.80 GRIN2B (0.62) CARM1PRMT6ACHEBACE1BCHE
SCHEMBL4266579 0.80 GRIN2B (0.62) CARM1PRMT6ACHEBACE1BCHE
SCHEMBL4266585 0.80 GRIN2B (0.62) CARM1PRMT6ACHEBACE1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251746-A1 USE OF AMINOQUINOLINE COMPOUNDS FOR HIGHER GENE INTEGRATION Cellectis SA (FR) 2023-10-04 EP disclosed
WO-2022112596-A1 USE OF AMINOQUINOLINE COMPOUNDS FOR HIGHER GENE INTEGRATION CELLECTIS SA (FR) 2022-06-02 WO disclosed