Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fluoroacetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.85 |
| ▸ | CA4 | P22748 | 6/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoroacetate SCHEMBL4908160 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 | |
| Fluoroacetate SCHEMBL6916946 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 | |
| Fluoroacetate SCHEMBL4908176 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 | |
| Fluoroacetate SCHEMBL13571787 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 | |
| Fluoroacetate SCHEMBL6916369 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 | |
| Fluoroacetate SCHEMBL6916626 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 | |
| Fluoroacetate SCHEMBL226060 | 0.92 | — | — | |
| Fluoroacetate SCHEMBL9958696 | 0.92 | — | — | |
| Fluoroacetate SCHEMBL6914898 | 0.92 | — | — | |
| Fluoroacetate SCHEMBL6915710 | 0.92 | CASP1 (0.85) | CASP1CA4FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805327-B1 | ANTIFOULING PAINT COMPOSITION | MITSUBISHI CHEM CORP (JP) | 2026-04-15 | — | — | EP | disclosed |
| WO-2025047885-A1 | RESIN COMPOSITION | 三菱ケミカル株式会社 | 2025-03-06 | — | — | WO | disclosed |
| US-11499069-B2 | (meth)acrylic copolymer, method for producing same, resin composition and antifouling paint composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-11-15 | — | — | US | disclosed |
| WO-2022210547-A1 | COMPOUND, POLYMER, AND ANTIFOULING PAINT COMPOSITION | 三菱ケミカル株式会社 | 2022-10-06 | — | — | WO | disclosed |
| US-11414508-B2 | Resin composition with a (meth)acrylic copolymer, antifouling paint composition, and method for producing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-08-16 | — | — | US | disclosed |
| EP-3604364-B1 | (METH)ACRYLIC COPOLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION AND ANTIFOULING PAINT COMPOSITION | MITSUBISHI CHEM CORP (JP) | 2021-09-08 | — | — | EP | disclosed |
| CN-106905802-B | Antifouling coating composition and coated article having coating film thereof | 关西涂料株式会社 | 2021-06-25 | — | — | CN | disclosed |
| EP-3805327-A1 | ANTIFOULING PAINT COMPOSITION | Mitsubishi Chemical Corporation (JP) | 2021-04-14 | — | — | EP | disclosed |
| US-20210079232-A1 | ANTIFOULING PAINT COMPOSITION | MITSUBISHI CHEMICAL CORPORATION (JP) | 2021-03-18 | — | — | US | disclosed |
| EP-3604364-A1 | (METH)ACRYLIC COPOLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION AND ANTIFOULING PAINT COMPOSITION | Mitsubishi Chemical Corporation (JP) | 2020-02-05 | — | — | EP | disclosed |
| EP-1006156-B1 | ANTIFOULING PAINT COMPOSITIONS | MITSUBISHI RAYON CO (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-1603979-A4 | ANTIFOULING PAINT COMPOSITION | MITSUBISHI RAYON CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| EP-1603979-A1 | ANTIFOULING PAINT COMPOSITION | Mitsubishi Rayon Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1167398-B1 | Metal-containing monomer dissolved mixture, metal-containing resin and antifouling paint composition | MITSUBISHI RAYON CO (JP) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004081121-A1 | ANTIFOULING PAINT COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 2004-09-23 | — | — | WO | disclosed |
| US-6727304-B2 | STORAGE STABILITY | MITSUBISHI RAYON CO., LTD. (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20020019457-A1 | Metal-containing monomer dissolved mixture, metal-containing resin and antifouling paint composition | MITSUBISHI RAYON CO., LTD. | 2002-02-14 | — | — | US | disclosed |
| EP-1167398-A2 | Metal-containing monomer dissolved mixture, metal-containing resin and antifouling paint composition | MITSUBISHI RAYON CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6177530-B1 | COPOLYMER OF MAGNESIUM, ZINC OR COPPER (METH)ACRYLATE | MITSUBISHI RAYON CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-1006156-A1 | ANTIFOULING PAINT COMPOSITIONS | Mitsubishi Rayon Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |